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Purification, characterization and immunogenicity assessment of glutaminase free L-asparaginase from Streptomyces brollosae NEAE-115

BACKGROUND: L-asparaginase is a potential therapeutic enzyme widely used in the chemotherapy protocols of pediatric and adult patients with acute lymphoblastic leukemia. However, its use has been limited by a high rate of hypersensitivity in the long-term used. Hence, there is a continuing need to s...

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Detalles Bibliográficos
Autores principales:	El-Naggar, Noura El-Ahmady, Deraz, Sahar F., El-Ewasy, Sara M., Suddek, Ghada M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108126/ https://www.ncbi.nlm.nih.gov/pubmed/30139388 http://dx.doi.org/10.1186/s40360-018-0242-1

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