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Exosomal double-stranded DNA as a biomarker for the diagnosis and preoperative assessment of pheochromocytoma and paraganglioma

Pheochromocytomas (PCCs) and paragangliomas (PGLs) are the most heritable endocrine tumors. Genetic testing for 12 driver susceptibility genes is recommended in all PCC and PGL cases. However, detection of somatic mutations in PCC and PGL remains unrealizable for genetic diagnosis and preoperative a...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Li, Ying, Guan, Xin, Zhao, Jingyuan, Shen, Liming, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108141/
https://www.ncbi.nlm.nih.gov/pubmed/30139385
http://dx.doi.org/10.1186/s12943-018-0876-z