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Benzyl isothiocyanate (BITC) triggers mitochondria-mediated apoptotic machinery in human cisplatin-resistant oral cancer CAR cells

Benzyl isothiocyanate (BITC), a component of dietary food, possesses a powerful anticancer activity. Previous studies have shown that BITC produces a large number of intracellular reactive oxygen species (ROS) and increases intracellular Ca(2+) release from endoplasmic reticulum (ER), leading to the...

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Detalles Bibliográficos
Autores principales: Lee, Chiu-Fang, Chiang, Ni-Na, Lu, Yao-Hua, Huang, Yu-Syuan, Yang, Jai-Sing, Tsai, Shih-Chang, Lu, Chi-Cheng, Chen, Fu-An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108226/
https://www.ncbi.nlm.nih.gov/pubmed/30141402
http://dx.doi.org/10.1051/bmdcn/2018080315