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Differentially Tolerized Mouse Antigen Presenting Cells Share a Common miRNA Signature Including Enhanced mmu-miR-223-3p Expression Which Is Sufficient to Imprint a Protolerogenic State

Dendritic cells (DCs) are pivotal for the induction and maintenance of antigen-specific tolerance and immunity. miRNAs mediate post-transcriptional gene regulation and control in part the differentiation and stimulation-induced immunogenic function of DCs. However, the relevance of miRNAs for the in...

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Detalles Bibliográficos
Autores principales: Bros, Matthias, Youns, Mahmoud, Kollek, Verena, Buchmüller, Diana, Bollmann, Franziska, Seo, Ean-Jeong, Schupp, Jonathan, Montermann, Evelyn, Usanova, Svetlana, Kleinert, Hartmut, Efferth, Thomas, Reske-Kunz, Angelika B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108336/
https://www.ncbi.nlm.nih.gov/pubmed/30174602
http://dx.doi.org/10.3389/fphar.2018.00915