Measurement of copy number variation in single cancer cells using rapid-emulsification digital droplet MDA

Uniform amplification of low-input DNA is important for applications across biology, including single-cell genomics, forensic science, and microbial and viral sequencing. However, the requisite biochemical amplification methods are prone to bias, skewing sequence proportions and obscuring signals re...

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Detalles Bibliográficos
Autores principales: Kim, Samuel C., Premasekharan, Gayatri, Clark, Iain C., Gemeda, Hawi B., Paris, Pamela L., Abate, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108428/
https://www.ncbi.nlm.nih.gov/pubmed/30147985
http://dx.doi.org/10.1038/micronano.2017.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108428/
https://www.ncbi.nlm.nih.gov/pubmed/30147985
http://dx.doi.org/10.1038/micronano.2017.18

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