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Deacetylase activity-independent transcriptional activation by HDAC2 during TPA-induced HL-60 cell differentiation

The human myeloid leukemia cell line HL-60 differentiate into monocytes following treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA). However, the mechanism underlying the differentiation of these cells in response to TPA has not been fully elucidated. In this study, we performed ChIP-seq pro...

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Detalles Bibliográficos
Autores principales: Jung, Hyeonsoo, Kim, Ji-Young, Kim, Kee-Beom, Chae, Yun-Cheol, Hahn, Yoonsoo, Kim, Jung-Woong, Seo, Sang-Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108480/
https://www.ncbi.nlm.nih.gov/pubmed/30142192
http://dx.doi.org/10.1371/journal.pone.0202935