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Adenoviral vector type 26 encoding Zika virus (ZIKV) M-Env antigen induces humoral and cellular immune responses and protects mice and nonhuman primates against ZIKV challenge

In 2015, there was a large outbreak of Zika virus (ZIKV) in Brazil. Despite its relatively mild impact on healthy adults, ZIKV infection during pregnancy has been associated with severe birth defects. Currently, there is no ZIKV vaccine available, but several vaccine candidates based on the ZIKV mem...

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Detalles Bibliográficos
Autores principales: Cox, Freek, van der Fits, Leslie, Abbink, Peter, Larocca, Rafael A., van Huizen, Ella, Saeland, Eirikur, Verhagen, Janneke, Peterson, Rebecca, Tolboom, Jeroen, Kaufmann, Baerbel, Schuitemaker, Hanneke, Barouch, Dan H., Zahn, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108497/
https://www.ncbi.nlm.nih.gov/pubmed/30142207
http://dx.doi.org/10.1371/journal.pone.0202820