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Physiologically Based Pharmacokinetic (PBPK) Modeling of the Bisphenols BPA, BPS, BPF, and BPAF with New Experimental Metabolic Parameters: Comparing the Pharmacokinetic Behavior of BPA with Its Substitutes

BACKGROUND: The endocrine disrupting chemical bisphenol A (BPA) has been facing stricter regulations in recent years. BPA analogs, such as the bisphenols S, F, and AF (BPS, BPF, and BPAF) are increasingly used as replacement chemicals, although they were found to exert estrogenic effects similar to...

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Detalles Bibliográficos
Autores principales: Karrer, Cecile, Roiss, Thomas, von Goetz, Natalie, Gramec Skledar, Darja, Peterlin Mašič, Lucija, Hungerbühler, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108829/
https://www.ncbi.nlm.nih.gov/pubmed/29995627
http://dx.doi.org/10.1289/EHP2739