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Effect of celastrol on toll-like receptor 4-mediated inflammatory response in free fatty acid-induced HepG2 cells

Toll-like receptor 4 (TLR4)-mediated immune and inflammatory signaling serves a pivotal role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Our previous study demonstrated that celastrol treatment was able to improve hepatic steatosis and inhibit the TLR4 signaling cascade pathway...

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Detalles Bibliográficos
Autores principales: Han, Li-Ping, Sun, Bei, Li, Chun-Jun, Xie, Yun, Chen, Li-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108865/
https://www.ncbi.nlm.nih.gov/pubmed/30015859
http://dx.doi.org/10.3892/ijmm.2018.3775