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Effect of celastrol on toll-like receptor 4-mediated inflammatory response in free fatty acid-induced HepG2 cells
Toll-like receptor 4 (TLR4)-mediated immune and inflammatory signaling serves a pivotal role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Our previous study demonstrated that celastrol treatment was able to improve hepatic steatosis and inhibit the TLR4 signaling cascade pathway...
Autores principales: | Han, Li-Ping, Sun, Bei, Li, Chun-Jun, Xie, Yun, Chen, Li-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108865/ https://www.ncbi.nlm.nih.gov/pubmed/30015859 http://dx.doi.org/10.3892/ijmm.2018.3775 |
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