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Alantolactone induces apoptosis and suppresses migration in MCF-7 human breast cancer cells via the p38 MAPK, NF-κB and Nrf2 signaling pathways

Human breast cancer is a malignant type of cancer with high prevalence. In the present study, the anticancer effects of alantolactone, a sesquiterpene lactone, on the human breast cancer cell line MF-7 were investigated in vitro. The MCF-7 cell morphology changed from diamond to round subsequent to...

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Detalles Bibliográficos
Autores principales: Liu, Jianli, Liu, Meijia, Wang, Shuai, He, Yin, Huo, Yapeng, Yang, Zhijun, Cao, Xiangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108867/
https://www.ncbi.nlm.nih.gov/pubmed/30015828
http://dx.doi.org/10.3892/ijmm.2018.3751