Inhibition of autophagy via activation of PI3K/Akt/mTOR pathway contributes to the protection of hesperidin against myocardial ischemia/reperfusion injury

Hesperidin has been reported to attenuate myocardial ischemia/reperfusion (I/R) injury; however, its effect on autophagy during myocardial I/R and the underlying mechanism remains unknown. The present study aimed to investigate whether hesperidin inhibited I/R-induced excessive myocardial autophagy...

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Detalles Bibliográficos
Autores principales: Li, Xuefei, Hu, Xiaorong, Wang, Jichun, Xu, Weipan, Yi, Chunfeng, Ma, Ruisong, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108872/
https://www.ncbi.nlm.nih.gov/pubmed/30066841
http://dx.doi.org/10.3892/ijmm.2018.3794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108872/
https://www.ncbi.nlm.nih.gov/pubmed/30066841
http://dx.doi.org/10.3892/ijmm.2018.3794

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