Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors

Neurofilament (NFL) proteins have recently been found to play unique roles in synapses. NFL is known to interact with the GluN1 subunit of N-methyl-d-aspartic acid (NMDAR) and be reduced in schizophrenia though functional consequences are unknown. Here we investigated whether the interaction of NFL...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Aidong, Veeranna, Sershen, Henry, Basavarajappa, Balapal S., Smiley, John F., Hashim, Audrey, Bleiwas, Cynthia, Berg, Martin, Guifoyle, David N., Subbanna, Shivakumar, Darji, Sandipkumar, Kumar, Asok, Rao, Mala V., Wilson, Donald A., Julien, Jean-Pierre, Javitt, Daniel C., Nixon, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109052/
https://www.ncbi.nlm.nih.gov/pubmed/30143609
http://dx.doi.org/10.1038/s41398-018-0194-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109052/
https://www.ncbi.nlm.nih.gov/pubmed/30143609
http://dx.doi.org/10.1038/s41398-018-0194-7

Ejemplares similares