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Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors
Neurofilament (NFL) proteins have recently been found to play unique roles in synapses. NFL is known to interact with the GluN1 subunit of N-methyl-d-aspartic acid (NMDAR) and be reduced in schizophrenia though functional consequences are unknown. Here we investigated whether the interaction of NFL...
Autores principales: | Yuan, Aidong, Veeranna, Sershen, Henry, Basavarajappa, Balapal S., Smiley, John F., Hashim, Audrey, Bleiwas, Cynthia, Berg, Martin, Guifoyle, David N., Subbanna, Shivakumar, Darji, Sandipkumar, Kumar, Asok, Rao, Mala V., Wilson, Donald A., Julien, Jean-Pierre, Javitt, Daniel C., Nixon, Ralph A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109052/ https://www.ncbi.nlm.nih.gov/pubmed/30143609 http://dx.doi.org/10.1038/s41398-018-0194-7 |
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