K(+) binding and proton redistribution in the E(2)P state of the H(+), K(+)-ATPase

The H(+), K(+)-ATPase (HKA) uses ATP to pump protons into the gastric lumen against a million-fold proton concentration gradient while counter-transporting K(+) from the lumen. The mechanism of release of a proton into a highly acidic stomach environment, and the subsequent binding of a K(+) ion nec...

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Detalles Bibliográficos
Autores principales: Dubey, Vikas, Han, Minwoo, Kopec, Wojciech, Solov’yov, Ilia A., Abe, Kazuhiro, Khandelia, Himanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109069/
https://www.ncbi.nlm.nih.gov/pubmed/30143663
http://dx.doi.org/10.1038/s41598-018-30885-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109069/
https://www.ncbi.nlm.nih.gov/pubmed/30143663
http://dx.doi.org/10.1038/s41598-018-30885-w

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