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K(+) binding and proton redistribution in the E(2)P state of the H(+), K(+)-ATPase
The H(+), K(+)-ATPase (HKA) uses ATP to pump protons into the gastric lumen against a million-fold proton concentration gradient while counter-transporting K(+) from the lumen. The mechanism of release of a proton into a highly acidic stomach environment, and the subsequent binding of a K(+) ion nec...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109069/ https://www.ncbi.nlm.nih.gov/pubmed/30143663 http://dx.doi.org/10.1038/s41598-018-30885-w |