Cargando…

Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation

AMP-activated protein kinase (AMPK) plays a key role in controlling energy metabolism in response to physiological and nutritional status. Although AMPK activation has been proposed as a promising molecular target for treating obesity and its related comorbidities, the use of pharmacological AMPK ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Min-Sik, Han, Hyun-Ji, Han, Su Yeon, Kim, Il Young, Chae, Sehyun, Lee, Choong-Sil, Kim, Sung Eun, Yoon, Seul Gi, Park, Jun-Won, Kim, Jung-Hoon, Shin, Soyeon, Jeong, Manhyung, Ko, Aram, Lee, Ho-Young, Oh, Kyoung-Jin, Lee, Yun-Hee, Bae, Kwang-Hee, Koo, Seung-Hoi, Kim, Jea-woo, Seong, Je Kyung, Hwang, Daehee, Song, Jaewhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109074/
https://www.ncbi.nlm.nih.gov/pubmed/30143610
http://dx.doi.org/10.1038/s41467-018-05721-4