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Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation
AMP-activated protein kinase (AMPK) plays a key role in controlling energy metabolism in response to physiological and nutritional status. Although AMPK activation has been proposed as a promising molecular target for treating obesity and its related comorbidities, the use of pharmacological AMPK ac...
Autores principales: | Lee, Min-Sik, Han, Hyun-Ji, Han, Su Yeon, Kim, Il Young, Chae, Sehyun, Lee, Choong-Sil, Kim, Sung Eun, Yoon, Seul Gi, Park, Jun-Won, Kim, Jung-Hoon, Shin, Soyeon, Jeong, Manhyung, Ko, Aram, Lee, Ho-Young, Oh, Kyoung-Jin, Lee, Yun-Hee, Bae, Kwang-Hee, Koo, Seung-Hoi, Kim, Jea-woo, Seong, Je Kyung, Hwang, Daehee, Song, Jaewhan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109074/ https://www.ncbi.nlm.nih.gov/pubmed/30143610 http://dx.doi.org/10.1038/s41467-018-05721-4 |
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