Cargando…

Characterization of membrane penetration and cytotoxicity of C9orf72-encoding arginine-rich dipeptides

Cell-penetrating peptides (CPPs) including arginine-rich peptides are attracting a lot of attention due to their potential as a novel intracellular drug delivery tool without substantial toxicity. On the other hand, disease-associated arginine-rich CPPs, such as poly-PR and poly-GR translated from C...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanekura, Kohsuke, Harada, Yuichiro, Fujimoto, Mao, Yagi, Takuya, Hayamizu, Yuhei, Nagaoka, Kentaro, Kuroda, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109075/
https://www.ncbi.nlm.nih.gov/pubmed/30143685
http://dx.doi.org/10.1038/s41598-018-31096-z