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The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption

The present study investigated the effects of conditional deletion of ephrinB1 in osteoprogenitor cells driven by the Osterix (Osx) promoter, on skeletal integrity in a murine model of ovariectomy-induced (OVX) osteoporosis. Histomorphometric and μCT analyses revealed that loss of ephrinB1 in sham O...

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Detalles Bibliográficos
Autores principales: Arthur, Agnieszka, Nguyen, Thao M., Paton, Sharon, Klisuric, Ana, Zannettino, Andrew C. W., Gronthos, Stan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109077/
https://www.ncbi.nlm.nih.gov/pubmed/30143786
http://dx.doi.org/10.1038/s41598-018-31190-2