RNAm expression profile of cancer marker genes in HepG2 cells treated with different concentrations of a new indolin-3-one from Pseudomonas aeruginosa

The present study tested the effects of a newly identified indolin-3-one compound (compound 1), produced by Pseudomonas aeruginosa, on HepG2 cells. The MTT assays demonstrated decreased metabolic activities in HepG2 cells treated with compound 1, with dose- and time-dependent intensifying effect, st...

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Detalles Bibliográficos
Autores principales: Benicio, Lucas Milanez, Simionato, Ane Stefano, Novello, Cláudio Roberto, Guimarães, Jeconias Rocha, Felicidade, Ingrid, de Oliveira, Admilton Gonçalves, de Mello, João Carlos Palazzo, Mantovani, Mário Sérgio, Chryssafidis, Andreas Lazaros, Andrade, Galdino, de Syllos Colus, Ilce Mara, de Oliveira, Marcelo Tempesta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109079/
https://www.ncbi.nlm.nih.gov/pubmed/30143666
http://dx.doi.org/10.1038/s41598-018-30893-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109079/
https://www.ncbi.nlm.nih.gov/pubmed/30143666
http://dx.doi.org/10.1038/s41598-018-30893-w

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