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RNAm expression profile of cancer marker genes in HepG2 cells treated with different concentrations of a new indolin-3-one from Pseudomonas aeruginosa
The present study tested the effects of a newly identified indolin-3-one compound (compound 1), produced by Pseudomonas aeruginosa, on HepG2 cells. The MTT assays demonstrated decreased metabolic activities in HepG2 cells treated with compound 1, with dose- and time-dependent intensifying effect, st...
Autores principales: | Benicio, Lucas Milanez, Simionato, Ane Stefano, Novello, Cláudio Roberto, Guimarães, Jeconias Rocha, Felicidade, Ingrid, de Oliveira, Admilton Gonçalves, de Mello, João Carlos Palazzo, Mantovani, Mário Sérgio, Chryssafidis, Andreas Lazaros, Andrade, Galdino, de Syllos Colus, Ilce Mara, de Oliveira, Marcelo Tempesta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109079/ https://www.ncbi.nlm.nih.gov/pubmed/30143666 http://dx.doi.org/10.1038/s41598-018-30893-w |
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