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Cytochrome C oxidase Inhibition and Cold Plasma-derived Oxidants Synergize in Melanoma Cell Death Induction

Despite striking advances in the treatment of metastasized melanoma, the disease is often still fatal. Attention is therefore paid towards combinational regimens. Oxidants endogenously produced in mitochondria are currently targeted in pre-clinical and clinical studies. Cytotoxic synergism of mitoch...

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Detalles Bibliográficos
Autores principales: Gandhirajan, Rajesh Kumar, Rödder, Katrin, Bodnar, Yana, Pasqual-Melo, Gabriella, Emmert, Steffen, Griguer, Corinne E., Weltmann, Klaus-Dieter, Bekeschus, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109085/
https://www.ncbi.nlm.nih.gov/pubmed/30143716
http://dx.doi.org/10.1038/s41598-018-31031-2