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Machine learning and image-based profiling in drug discovery

The increase in imaging throughput, new analytical frameworks and high-performance computational resources open new avenues for data-rich phenotypic profiling of small molecules in drug discovery. Image-based profiling assays assessing single-cell phenotypes have been used to explore mechanisms of a...

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Detalles Bibliográficos
Autores principales: Scheeder, Christian, Heigwer, Florian, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109111/
https://www.ncbi.nlm.nih.gov/pubmed/30159406
http://dx.doi.org/10.1016/j.coisb.2018.05.004