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Pan-cancer analysis of neoepitopes

Somatic variations are frequent and important drivers in cancers. Amino acid substitutions can yield neoantigens that are detected by the immune system. Neoantigens can lead to immune response and tumor rejection. Although neoantigen load and occurrence have been widely studied, a detailed pan-cance...

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Detalles Bibliográficos
Autores principales: Teku, Gabriel N., Vihinen, Mauno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109115/
https://www.ncbi.nlm.nih.gov/pubmed/30143704
http://dx.doi.org/10.1038/s41598-018-30724-y