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Mitochondrial DNA copy number is associated with psychosis severity and anti-psychotic treatment

Mitochondrial pathology has been implicated in the pathogenesis of psychotic disorders. A few studies have proposed reduced leukocyte mitochondrial DNA (mtDNA) copy number in schizophrenia and bipolar disorder type I, compared to healthy controls. However, it is unknown if mtDNA copy number alterati...

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Detalles Bibliográficos
Autores principales: Kumar, Parvin, Efstathopoulos, Paschalis, Millischer, Vincent, Olsson, Eric, Wei, Ya Bin, Brüstle, Oliver, Schalling, Martin, Villaescusa, J. Carlos, Ösby, Urban, Lavebratt, Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109159/
https://www.ncbi.nlm.nih.gov/pubmed/30143692
http://dx.doi.org/10.1038/s41598-018-31122-0