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Zika virus impairs the development of blood vessels in a mouse model of congenital infection

Zika virus (ZIKV) is associated with brain development abnormalities such as primary microcephaly, a severe reduction in brain growth. Here we demonstrated in vivo the impact of congenital ZIKV infection in blood vessel development, a crucial step in organogenesis. ZIKV was injected intravenously in...

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Detalles Bibliográficos
Autores principales: Garcez, P. P., Stolp, H. B., Sravanam, S., Christoff, R. R., Ferreira, J. C. C. G., Dias, A. A., Pezzuto, P., Higa, L. M., Barbeito-Andrés, J., Ferreira, R. O., Andrade, C. B V., Siqueira, M., Santos, T. M. P., Drumond, J., Hoerder-Suabedissen, A., de Lima, C. V. F., Tovar-Moll, F., Lopes, R. T., Fragel-Madeira, L., Lent, R., Ortiga-Carvalho, T. M., Stipursky, J., Bellio, M., Tanuri, A., Molnár, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109170/
https://www.ncbi.nlm.nih.gov/pubmed/30143723
http://dx.doi.org/10.1038/s41598-018-31149-3