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Identification of beagle food taking patterns and protocol for food effects evaluation on bioavailability

Food is a known primary role to the exposure of the drugs orally administered. Since each animal may have unique food taking pattern and it is difficult to manipulate the food taking to animals, there lacks rationalized protocol for the food effects in pre-clinic study. The objective of this study w...

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Detalles Bibliográficos
Autores principales: Zhang, Guoqing, Wang, Caifen, Wu, Li, Xu, Jian, Hu, Xiaoxiao, Shakya, Shailendra, He, Yuanzhi, Ren, Xiaohong, Chen, Weidong, Zhang, Jiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109188/
https://www.ncbi.nlm.nih.gov/pubmed/30143653
http://dx.doi.org/10.1038/s41598-018-30937-1