Mitotane in the treatment of childhood adrenocortical carcinoma: a potent endocrine disruptor

Adrenocortical carcinoma (ACC) during childhood is a rare malignant tumor that frequently results in glucocorticoid and/or androgen excess. When there are signs of microscopic or macroscopic residual disease, adjuvant therapy is recommended with mitotane, an adrenolytic and cytotoxic drug. In additi...

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Detalles Bibliográficos
Autores principales: Oddie, Philip D, Albert, Benjamin B, Hofman, Paul L, Jefferies, Craig, Laughton, Stephen, Carter, Philippa J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Unusual Effects of Medical Treatment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109212/
https://www.ncbi.nlm.nih.gov/pubmed/30159150
http://dx.doi.org/10.1530/EDM-18-0059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109212/
https://www.ncbi.nlm.nih.gov/pubmed/30159150
http://dx.doi.org/10.1530/EDM-18-0059

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