Loss of Gαq impairs regulatory B-cell function

BACKGROUND: Recent studies have shown a crucial role of Gαq in immune regulation, but how Gαq modulates regulatory B-cell (Breg) function is still unclear. We address this here. METHODS: CD19(+)IL-10(+) Bregs of wild-type (WT) and Gnaq(−/−) mice were analyzed by flow cytometry after stimulation by l...

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Detalles Bibliográficos
Autores principales: He, Yan, Yuan, Xiaoqing, Li, Yan, Zhong, Chunlian, Liu, Yuan, Qian, Hongyan, Xuan, Jingxiu, Duan, Lihua, Shi, Guixiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109260/
https://www.ncbi.nlm.nih.gov/pubmed/30143054
http://dx.doi.org/10.1186/s13075-018-1682-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109260/
https://www.ncbi.nlm.nih.gov/pubmed/30143054
http://dx.doi.org/10.1186/s13075-018-1682-0

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