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Whole blood profiling of leprosy type 1(reversal) reactions highlights prominence of innate immune response genes

BACKGROUND: The major factors contributing for nerve damage and permanent disabilities in leprosy are type 1 or reversal reactions (RR) and type 2 or erythema nodosum leprosum (ENL). Gene profiling of leprosy reactions have shown that different pathways are activated during the course of reactions,...

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Detalles Bibliográficos
Autores principales: Rêgo, Jamile Leão, de Lima Santana, Nadja, Machado, Paulo Roberto Lima, Ribeiro-Alves, Marcelo, de Toledo-Pinto, Thiago Gomes, Castellucci, Léa Cristina, Moraes, Milton Ozório
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109344/
https://www.ncbi.nlm.nih.gov/pubmed/30143000
http://dx.doi.org/10.1186/s12879-018-3348-6