Cargando…

Exploring the pre-immune landscape of antigen-specific T cells

BACKGROUND: Adaptive immune responses to newly encountered pathogens depend on the mobilization of antigen-specific clonotypes from a vastly diverse pool of naive T cells. Using recent advances in immune repertoire sequencing technologies, models of the immune receptor rearrangement process, and a d...

Descripción completa

Detalles Bibliográficos
Autores principales: Pogorelyy, Mikhail V., Fedorova, Alla D., McLaren, James E., Ladell, Kristin, Bagaev, Dmitri V., Eliseev, Alexey V., Mikelov, Artem I., Koneva, Anna E., Zvyagin, Ivan V., Price, David A., Chudakov, Dmitry M., Shugay, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109350/
https://www.ncbi.nlm.nih.gov/pubmed/30144804
http://dx.doi.org/10.1186/s13073-018-0577-7