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Activation of neuronal N-methyl-d-aspartate receptor plays a pivotal role in Japanese encephalitis virus-induced neuronal cell damage

BACKGROUND: Overstimulation of glutamate receptors, especially neuronal N-methyl-d-aspartate receptor (NMDAR), mediates excitatory neurotoxicity in multiple neurodegenerative diseases. However, the role of NMDAR in the regulation of Japanese encephalitis virus (JEV)-mediated neuropathogenesis remain...

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Detalles Bibliográficos
Autores principales: Chen, Zheng, Wang, Xugang, Ashraf, Usama, Zheng, Bohan, Ye, Jing, Zhou, Dengyuan, Zhang, Hao, Song, Yunfeng, Chen, Huanchun, Zhao, Shuhong, Cao, Shengbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109458/
https://www.ncbi.nlm.nih.gov/pubmed/30144801
http://dx.doi.org/10.1186/s12974-018-1280-8