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Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs

The advanced-stage colon cancer spreads from primary tumor site to distant organs where the colon-unassociated stromal population provides a favorable niche for the growth of tumor cells. The heterocellular interactions between colon cancer cells and colon-unassociated fibroblasts at distant metasta...

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Detalles Bibliográficos
Autores principales: Agrawal, Khushboo, Das, Viswanath, Táborská, Natálie, Gurský, Ján, Džubák, Petr, Hajdúch, Marián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109465/
https://www.ncbi.nlm.nih.gov/pubmed/30158986
http://dx.doi.org/10.1155/2018/6013728