Anti-IL-22 Antibody Attenuates Acute Graft-versus-Host Disease via Increasing Foxp3(+) T Cell through Modulation of CD11b(+) Cell Function

Transfer of splenocytes isolated from B6 mice into normal B6D2F1 mice induces acute graft-versus-host disease (aGVHD), resulting in the expansion of donor cytotoxic T lymphocytes that eliminate recipient B cells. The cytokine IL-22, secreted by Th1 cells, Th17 cells, and innate immune cells, is stru...

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Detalles Bibliográficos
Autores principales: Wu, Jianbo, Gu, Jian, Zhou, Shun, Lu, Hao, Lu, Yunjie, Lu, Ling, Wang, Xuehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109487/
https://www.ncbi.nlm.nih.gov/pubmed/30159338
http://dx.doi.org/10.1155/2018/1605341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109487/
https://www.ncbi.nlm.nih.gov/pubmed/30159338
http://dx.doi.org/10.1155/2018/1605341

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