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Gut-microbiome related LCT genotype and 2-year changes in body composition and fat distribution: the POUNDS Lost Trial

BACKGROUND/OBJECTIVES: Gut microbiome regulates host energy metabolism and adiposity. A recent study identified a genome-wide significant variant in the lactase (LCT) gene that determines gut microbiome abundance. We investigated whether the LCT variant influenced long-term changes in adiposity amon...

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Detalles Bibliográficos
Autores principales: Heianza, Yoriko, Sun, Dianjianyi, Ma, Wenjie, Zheng, Yan, Champagne, Catherine M., Bray, George A., Sacks, Frank M., Qi, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109621/
https://www.ncbi.nlm.nih.gov/pubmed/29568104
http://dx.doi.org/10.1038/s41366-018-0046-9