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A Gene-Based Positive Selection Detection Approach to Identify Vaccine Candidates Using Toxoplasma gondii as a Test Case Protozoan Pathogen

Over the last two decades, various in silico approaches have been developed and refined that attempt to identify protein and/or peptide vaccines candidates from informative signals encoded in protein sequences of a target pathogen. As to date, no signal has been identified that clearly indicates a p...

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Detalles Bibliográficos
Autores principales: Goodswen, Stephen J., Kennedy, Paul J., Ellis, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109633/
https://www.ncbi.nlm.nih.gov/pubmed/30177953
http://dx.doi.org/10.3389/fgene.2018.00332