A novel approach to target hypoxic cancer cells via combining β-oxidation inhibitor etomoxir with radiation

BACKGROUND: Hypoxia in tumors is associated with resistance towards various therapies including radiotherapy. In this study, we assessed if hypoxia in cancer spheres could be effectively reduced by adding etomoxir (a β-oxidation inhibitor) immediately after cell irradiation. METHODS: We employed can...

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Detalles Bibliográficos
Autores principales: Dheeraj, Arpit, Agarwal, Chapla, Schlaepfer, Isabel R, Raben, David, Singh, Rana, Agarwal, Rajesh, Deep, Gagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109663/
https://www.ncbi.nlm.nih.gov/pubmed/30175155
http://dx.doi.org/10.2147/HP.S163115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109663/
https://www.ncbi.nlm.nih.gov/pubmed/30175155
http://dx.doi.org/10.2147/HP.S163115

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