Development, validation and application of a novel HPLC-MS/MS method for the quantification of atorvastatin, bisoprolol and clopidogrel in a large cardiovascular patient cohort

Cardiovascular disease is a leading cause of morbidity, mortality, and healthcare expenditure worldwide. Importantly, there is interindividual variation in response to cardiovascular medications, leading to variable efficacy and adverse events. Therefore a rapid, selective, sensitive and reproducibl...

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Detalles Bibliográficos
Autores principales: Turner, Richard Myles, Fontana, Vanessa, Bayliss, Mark, Whalley, Sarah, Santoyo Castelazo, Anahi, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109775/
https://www.ncbi.nlm.nih.gov/pubmed/30005242
http://dx.doi.org/10.1016/j.jpba.2018.06.062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109775/
https://www.ncbi.nlm.nih.gov/pubmed/30005242
http://dx.doi.org/10.1016/j.jpba.2018.06.062

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