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Development, validation and application of a novel HPLC-MS/MS method for the quantification of atorvastatin, bisoprolol and clopidogrel in a large cardiovascular patient cohort
Cardiovascular disease is a leading cause of morbidity, mortality, and healthcare expenditure worldwide. Importantly, there is interindividual variation in response to cardiovascular medications, leading to variable efficacy and adverse events. Therefore a rapid, selective, sensitive and reproducibl...
Autores principales: | Turner, Richard Myles, Fontana, Vanessa, Bayliss, Mark, Whalley, Sarah, Santoyo Castelazo, Anahi, Pirmohamed, Munir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109775/ https://www.ncbi.nlm.nih.gov/pubmed/30005242 http://dx.doi.org/10.1016/j.jpba.2018.06.062 |
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