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Sorting Out the Role of α-Synuclein in Retromer-Mediated Endosomal Protein Sorting
Retromer is a phylogenetically conserved, multisubunit coat complex that controls endosomal protein trafficking and sorting. Mutations in the retromer gene VPS35 cause late-onset Parkinson disease, suggesting that trafficking defects cause neurodegeneration. Sorting nexins assist retromer to guide c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109851/ https://www.ncbi.nlm.nih.gov/pubmed/30158827 http://dx.doi.org/10.1177/1179069518796215 |