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Sorting Out the Role of α-Synuclein in Retromer-Mediated Endosomal Protein Sorting

Retromer is a phylogenetically conserved, multisubunit coat complex that controls endosomal protein trafficking and sorting. Mutations in the retromer gene VPS35 cause late-onset Parkinson disease, suggesting that trafficking defects cause neurodegeneration. Sorting nexins assist retromer to guide c...

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Detalles Bibliográficos
Autores principales:	Patel, Dhaval, Witt, Stephan N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109851/ https://www.ncbi.nlm.nih.gov/pubmed/30158827 http://dx.doi.org/10.1177/1179069518796215

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