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Structural and functional analysis of cystatin E reveals enzymologically relevant dimer and amyloid fibril states

Protein activity is often regulated by altering the oligomerization state. One mechanism of multimerization involves domain swapping, wherein proteins exchange parts of their structures and thereby form long-lived dimers or multimers. Domain swapping has been specifically observed in amyloidogenic p...

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Detalles Bibliográficos
Autores principales:	Dall, Elfriede, Hollerweger, Julia C., Dahms, Sven O., Cui, Haissi, Häussermann, Katharina, Brandstetter, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109925/ https://www.ncbi.nlm.nih.gov/pubmed/29967063 http://dx.doi.org/10.1074/jbc.RA118.002154

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