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Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer’s disease

INTRODUCTION: Individuals in early stages of Alzheimer’s disease are a targeted population for secondary prevention trials aimed at preserving normal cognition. Understanding within-person biomarkers) change over time is critical for trial enrollment and design. METHODS: Longitudinal cerebrospinal f...

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Detalles Bibliográficos
Autores principales: Sutphen, Courtney L., McCue, Lena, Herries, Elizabeth M., Xiong, Chengjie, Ladenson, Jack H., Holtzman, David M., Fagan, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110083/
https://www.ncbi.nlm.nih.gov/pubmed/29580670
http://dx.doi.org/10.1016/j.jalz.2018.01.012