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Contribution of Calpain and Caspases to Cell Death in Cultured Monkey RPE Cells
PURPOSE: AMD is the leading cause of human vision loss after 65 years of age. Several mechanisms have been proposed: (1) age-related failure of the choroidal vasculature leads to loss of RPE; (2) RPE dysfunctions due to accumulation of phagocytized, but unreleased A2E (N-retinylidene-N-retinylethano...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110128/ https://www.ncbi.nlm.nih.gov/pubmed/29053764 http://dx.doi.org/10.1167/iovs.17-22325 |