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Contribution of Calpain and Caspases to Cell Death in Cultured Monkey RPE Cells

PURPOSE: AMD is the leading cause of human vision loss after 65 years of age. Several mechanisms have been proposed: (1) age-related failure of the choroidal vasculature leads to loss of RPE; (2) RPE dysfunctions due to accumulation of phagocytized, but unreleased A2E (N-retinylidene-N-retinylethano...

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Detalles Bibliográficos
Autores principales:	Nakajima, Emi, Hammond, Katherine B., Hirata, Masayuki, Shearer, Thomas R., Azuma, Mitsuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110128/ https://www.ncbi.nlm.nih.gov/pubmed/29053764 http://dx.doi.org/10.1167/iovs.17-22325

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