Gastrodin induced HO-1 and Nrf2 up-regulation to alleviate H(2)O(2)-induced oxidative stress in mouse liver sinusoidal endothelial cells through p38 MAPK phosphorylation

Nuclear factor erythroid-related factor 2 (Nrf2) has been implicated in several detoxifying and antioxidant defense processes. Nrf2-mediated heme oxygenase-1 (HO-1) expression was demonstrated to play a key role against oxidative stress. Gastrodin (GSTD) is a well-known active compound isolated from...

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Detalles Bibliográficos
Autores principales: Zhang, Hongbin, Yuan, Bo, Huang, Hanfei, Qu, Siming, Yang, Shikun, Zeng, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110350/
https://www.ncbi.nlm.nih.gov/pubmed/30156611
http://dx.doi.org/10.1590/1414-431X20187439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110350/
https://www.ncbi.nlm.nih.gov/pubmed/30156611
http://dx.doi.org/10.1590/1414-431X20187439

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