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Gastrodin induced HO-1 and Nrf2 up-regulation to alleviate H(2)O(2)-induced oxidative stress in mouse liver sinusoidal endothelial cells through p38 MAPK phosphorylation
Nuclear factor erythroid-related factor 2 (Nrf2) has been implicated in several detoxifying and antioxidant defense processes. Nrf2-mediated heme oxygenase-1 (HO-1) expression was demonstrated to play a key role against oxidative stress. Gastrodin (GSTD) is a well-known active compound isolated from...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Associação Brasileira de Divulgação Científica
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110350/ https://www.ncbi.nlm.nih.gov/pubmed/30156611 http://dx.doi.org/10.1590/1414-431X20187439 |