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Exposure–Response Analysis of Micafungin in Neonatal Candidiasis: Pooled Analysis of Two Clinical Trials

BACKGROUND: Neonatal candidiasis causes significant morbidity and mortality in high risk infants. The micafungin dosage regimen of 10 mg/kg established for the treatment of neonatal candidiasis is based on a laboratory animal model of neonatal hematogenous Candida meningoencephalitis and pharmacokin...

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Detalles Bibliográficos
Autores principales: Kovanda, Laura L., Walsh, Thomas J., Benjamin, Daniel K., Arrieta, Antonio, Kaufman, David A., Smith, P. Brian, Manzoni, Paolo, Desai, Amit V., Kaibara, Atsunori, Bonate, Peter L., Hope, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110378/
https://www.ncbi.nlm.nih.gov/pubmed/29762386
http://dx.doi.org/10.1097/INF.0000000000001957

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