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Exposure–Response Analysis of Micafungin in Neonatal Candidiasis: Pooled Analysis of Two Clinical Trials
BACKGROUND: Neonatal candidiasis causes significant morbidity and mortality in high risk infants. The micafungin dosage regimen of 10 mg/kg established for the treatment of neonatal candidiasis is based on a laboratory animal model of neonatal hematogenous Candida meningoencephalitis and pharmacokin...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110378/ https://www.ncbi.nlm.nih.gov/pubmed/29762386 http://dx.doi.org/10.1097/INF.0000000000001957 |